Irina Shidou/Relationships

Issei Hyoudou
Prior to the series, Irina has known Issei since childhood and has had a crush on him since then. She does care for Issei a great deal because even when Issei was reincarnated as a Devil and had changed into a pervert, she still loved him no matter what. In Volume 9, she was incited to mate with Issei by Xenovia by helping to strengthen Heaven's forces, nearly turning into a Fallen Angel in the process.

In Volume 12, she showed her feelings of love towards Issei when she found out about his "death". She is strongly in love with Issei but her status as an Angel is impeding her relationship because Angels are forbidden to fall in love. In Volume 14, however, it is revealed that there is a way for angels to mate with humans without "falling". This method was a way for Heaven to bolster its numbers after the Great War that decimated a majority of their forces. In order to pull this off, however, both parties' thoughts must remain chaste and pure while committing the carnal act; a feat which Issei deems nigh impossible for a perverse Devil-Dragon hybrid like him. Still, Irina herself has shown willingness to try it, and sometimes even considers "falling" so long as it means being with Issei.

Xenovia
She is a very good friend to her, and missed her when she became a reincarnated Devil. Together with Asia, they form the Church Trio because they are often seen together praying with her.

Asia Argento
She is a very close friend to her and they, along with Xenovia, form the Church Trio because they are often seen praying together. She is very supportive of Asia's relationship with Issei due to her purity and Issei's dedication and love for her. Xenovia and her are protective of Asia and always look out for her.

Michael
He is the spiritual support for her since she found out that God died. He is also her leader as she is one of 'his' Brave Saints. Irina is also very loyal to him.

Dulio Gesualdo
Irina and Dulio has never interacted with each other but it is shown that Irina respects Dulio for his skills and position, calling him "Dulio-sama".