User blog comment:Crimson and Darkness/Volume 24 discussion blog/@comment-28626666-20180102035032/@comment-29963364-20180102060829

Lucifer used Lilith to create hundreds of thousands of [Original Devils], and he picked the 72 strongest ones to be the "First [72 Pillars]" (Zekram, the first Agares, the first Gremory, etc.).

Their are also several [Extra Demon] Clans (we only know of Lucifuge, Abaddon, Belphagor, and Nebiros), all of whome directly serve the Original [Four Satans].

We don't know if Lucifer created the other three Original Satans.

I highly, HIGHLY doubt that these created Devils were babies when they were created. Lucifer wanted an army to fight against God & His Angels, and the Fallen Angels. There's no way that he would go through the trouble of making hundreds of thousands of babies and wait for them to grow into adults. He would "create" them as adults from the start.

I n one of the spoilers revealed (I don't remember who posted it, but it was recent), when Hades and his Grim Reapers found Rizevims' hidden lab, they found the "lump of flesh" that was Lilith, and thousands of pastry dishes that were filled with "samples."

My current theory is that the Original Lucifer took pieces of Lilith's flesh, and used a combination of Magic and Science to make the "samples" grow and morph into the [Original Devils] in their mature (late teen/young adult) form, and Hades is now using the same method (but improved by Rizevim) to create his army of [NewDevils].

So, since these [New Devils] were created using the same (albeit improved) method as the [Original Devils], they aren't "artificial" at all.

You could say the [Original Devils] are "Devil-1.0", the [Reincarnated Devils] are "Devil-1.2," and the [New Devils] are "Devil-2.0."