User blog comment:DeathGodPrayer/re Talk about season 2/@comment-98.77.248.132-20120425221129/@comment-111.68.59.100-20120426045629

Man I know the answer but i suddenly forgot but all i know that Great Red became the teacher of Issei maybe in that time they build some relationship or something.

Or maybe Ophis beg for Great Red to help her resurrect issei :]