User blog comment:B214/Volume 21 info & spoilers/@comment-83.26.184.132-20160624091556/@comment-93.105.241.146-20160624105030

I really doubt Ophis can actually have kids considering it's actually genderless. It probably could have sex with Iseei in it's female form but it's unlikely to result in pregnancy. I mean this would be getting a bit wierd then cinsidering it can turn into a male too. So then what? It can also impregnate a female? That would make Ophis a hermaphrodite and it could probably get pregnant on it's own.

So no that's really a bad idea if you ask me.