User blog comment:B214/DxD Updates 3/@comment-5384276-20200122191217

It seems that in regards to Alpheca Tyrant and Ise's loss of perversion:

Alpheca Tyrant seems to have the ability to affect concept at least in living beings so this explains Ise's sudden shame at echii behavior. It is likely Hades brainwashes her and makes her shoot Ise as revenge for DxD taking away the Netherworld from him. Also seems to hint that she is somehow resposible for Fake Ddraig & Albion.