User blog comment:B214/Question and Answers 6/@comment-185.112.105.215-20161231124330/@comment-1359322-20161231144955

Ophis' blessings can come in many form though, the snakes may be one of them. It won't be surprising if both Ise and Vali has a small portion of Ophis' powers in them due to that blessing.

As for Saji and Sairaorg, they might not be close enough to Ophis for that. Vali used to talk a lot with Ophis during their time in Khaos Brigade so they do have a level of closeness/friendship between them.