User blog comment:Jopjopjop/Volume 20 Spoilers/@comment-54.158.126.18-20150723000735/@comment-26285797-20150723133301

@anon I'm not so sure. Even with Great Red's flesh, Issei said that trying to handle even the finite power that Ophis had was incredibly taxing. I believe the form is stable, just has an immense stamina consumption. Adding Lilith's power to Ophis or having her give Issei power as well could destroy him. Remember, this the power of infinity we're talking about here, so the price could be incredibly steep, such as the loss of his SG after deactivation or something along those lines. It has to be worse than when Ddraig feel asleep.