User blog comment:B214/Talk About What You Want! 2/@comment-24098614-20140602220824/@comment-24866657-20140604100407

I don't quite understand what you try to imply, since Ophis hasn't given Rias any blessing, as far as we know for now. In canon the only ones showed that they had been blessed were Asia and Irina, as for Issei, it's not a blessing but a karma that no god can help him purify, like Ophis sticking to him for eternal.