User blog comment:TheBlueSlug/Who should issei end up with?/@comment-174.119.241.202-20131112181547/@comment-9339850-20131112182213

if we're being optimistic, probably 1 or 2 each, that is if he actually gets every girl pregnant 0__o

But it'll take time given the Devil's low birthrate; Irina probably has the highest chance of having a child, though the risk of her falling in the "Conceiving" Ritual is a sort of counter-balance